The endocannabinoid system was discovered by Israeli researcher Dr. Ralph Mechoulam in the mid-1990s. The human body has two types of cannabinoid receptors which play an important role in your immune system, glucose metabolism, insulin resistance and blood formation. These receptors also play a role in cognition, memory, mood, motor function, sensory, autonomic and neurocrine responses. They are responsible for inflammation's effect on your body, and vomiting, nausea, hunger and appetite control. They are configured to accept only cannabinoids like CBD (cannabidiol), such as that found in hemp oil extract.